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We discuss metabolism and detoxification strategies of heavy metals and metalloid, with emphasis on the use of transcriptomics, metabolomics, and proteomics

For instance, in tumors harboring p53 72P variant, PSAT1 interacts competitively with the mutant without relying on its enzymatic function, promoting the nuclear import of peroxisome proliferator-activated receptor- coactivator 1 (PGC-1) and thereby increasing mitochondrial biogenesis, oxidative phosphorylation (OXPHOS), and TCA cycle processes (Fig

RNA isolation and RNA sequencing analysis Total RNA was isolated from the same subset of adipose tissue samples used for genome-wide DNA methylation analysis ( n = 8

doi: 10.1038/ajg.2012.219

and upregulation of Q9CQN1 and HSP 90-alpha (P07901)